You know why? Because at 150mg a day it's giving me really bad diarrhea. I know, lovely right? My family doctor has told me to go back down to 100mg. She also tried to draw blood to run tests just to check and make sure it really is the Pristiq, but guess what? I'm too dehydrated from the diarrhea. Every time they poked the needle in a vein, it collapsed. I came home with four neon pink gauze bandages on my arms, and at least two more puncture marks. I'm getting an I.V. tomorrow. I hate this.